During the experiments with the help of new technology, it was possible to restore sight to a blind person from birth, a rabbit that did not have a cornea. Already everything is ready for the beginning of real trials on patients. According to Nishid, in the next three years there will be an opportunity to carry out operations to restore the damaged cornea.
The new project of Japanese scientists is a continuation of the work begun in 2005, when it came to realize that they can get stem cells from the most common cells of blood or skin using some manipulations with DNA. Six years later, two researchers, Shinya Yamanaka and John Gardon, were awarded the Nobel Prize for this. The created biomaterial was called “induced pluripotent stem cells” or iPS.
Koji Nishida and his colleagues were able to stimulate the participation of pluripotent cells in the formation of the so-called protoglaze, from which it is then possible to extract individual tissues. Growth of cells was carried out in a petri dish, where the correct combination of proteins and other substances was used as their basis.
In fact, the protoglossus consists of four rings of different types of cells, which are then transformed into different parts of the eye.